If you don't like any of them please suggest another option:)???

I think there could be several options:

1)It will either be one dies and the other survives, since by ending the series on both main characters dying will not really be closure, since it doesn't show life continuing (for at least one character)

2)Both survive, both quit hunting, or both continuing hunting, (I don't think 1 will continue hunting while the other is not, since they are usually there for each other)

3)Or open-ended ending (which I hope they don't pursue because for such an epic series, I think the conclusion should provide some degree of closure)

I just don't want it to end! It should have a lot more seasons!!!!

well jared allways said he wanted them to die so I think they should but I do not think that happen they will move on and do a movie.

why you gonna be talkin' bout endings? :(

No big stuff, the entire world doesn't need saving, and they're back to hunting monsters and ghosts like S1. I'd hope Cas would stick around, and Destiel would happen.

I want Sam and Dean to live forever... if they died I would ball my eyes out!!!!!!!!

I think it'd either be both dying, or one dying and the other quitting hunting (like the end of season 5 which could have been a permanent ending).