I was going to list them but then I thought it'd be easier to add my video I've just made that happens to be of my 25 favourite couples x

1. Brooke & Lucas (One Tree Hill)
2. Shane & Carmen (The L Word)
3. Emily & Naomi (Skins)
4. Mini & Franky (Skins)
5. Cooper & Charlotte (Private Practice)
6. Quinn & Rachel (Glee)
7. Marissa & Alex (The OC)
8. Blair & Chuck (Gossip Girl)
9. Sid/Cassie (Skins)
10. Finn/Quinn (Glee)
11. Puck/Rachel (Glee)
12. Puck/Quinn (Glee)
13. Caroline & Tyler (The Vampire Diaries)
14. Bill/Sookie (True Blood)
15. Aurora/Van (Outrageous Fortune)
16. Jenny/Nate (Gossip Girl)
17. Stefan/Katherine (The Vampire Diaires)
18. Krista/Chase (Blade The Series)
19. Dan/Serena (Gossip Girl)
20. Damon/Elena (The Vampire Diaries)
21. Cook/Effy (Skins)
22. Freddie/Effy (Skins)
23. Castle/Beckett (Castle)
24. Veronica/Logan (Veronica Mars)
25. Chris/Jal (Skins)

missed:
Spike/Buffy (Buffy The Vampire Slayer)
Willow/Tara (Buffy The Vampire Slayer)
Chuck/Sarah (Chuck)
Hermione/Ron (Harry Potter)
Hermione/Harry (Harry Potter)
Stefan/Caroline (The Vampire Diaries)
Jake/Peyton (One Tree Hill)
Eric/Sookie (True Blood)
Dan/Blair (Gossip Girl)

Probably a dozen more, but that's my list.

Since this is favorite couples of all time I have, of course, included my ships that are no longer plausible. By non-plausible, I mean that one or both characters where written off the show, or the show ended without the characters getting together. The starred ones are non-plausible.

In no particular order:

House and Cuddy (House)
Chase and Thirteen (House)
Kutner and Thirteen (House)*
Wilson and Cameron (House)*
Booth and Brennan (Bones)
Peter and Olivia (Fringe)
Charlie and Olivia (Fringe)*
Cal and Gillian (Lie to Me)
Loker and Torres (Lie to Me)
Chance and Ilsa (Human Target)
Jack and Renee (24)
Tony and Michelle (24)
Milo and Nadia (24)*
Shawn and Juliet (Psych)
Castle and Beckett (Castle)
Carter and Allison (Eureka)
Carter and Jo (Eureka)
Tony and Ziva (NCIS)
Tony and Kate (NCIS)*
McGee and Abby (NCIS)
Hotch and Emily (Criminal Minds)
Reid and JJ (Criminal Minds)*
Mac and Stella (CSI:NY)*
Danny and Aiden (CSI:NY)*
Mal and Inara (Firefly)*

Sooooo bitter about that last one...and the third-to-last one.

Annie & Liam (90210)
chuck & Blair(GG)
Emily&Damon (MIOBI)
Amy&Riky (TSLOAT)
Aria & Mr Fitz (pll)
casey & cappy(Greek)
chuck & Sarah (chuck)
Brook&Julian(oth)
Lucas & Peyton (oth)
Nathan & Haley (oth)
Clay & Quinn (oth)
Finn&Rachel(Glee)
Stefan & Elena (vampire Diaries)
clark & Lois (smallville)
Kris and Jr (wildfire)
joey & Pacy (dawson`s creek)
seth&Summer(oc)
Marissa&Ryan (oc)
Max & Liz ( Roswell)
Brandon & Kelly(bev hills 90210)
Effy&Freddie(Skins)
veronica & Logan ( veronica Mars)
House & cuddy (House)
Echo & Paul (Dollhouse)
Buffy&Angel (BTVS)

1) Niles & Daphne – Frasier
2) Meredith & Derek – Grey’s Anatomy
3) House & Cuddy – House M.D
4) Will & Emma – Glee
5) Susan & Mike – Desperate Housewives
6) Luke & Lorelai – Gilmore Girls
7) Fran & Max – The Nanny
8) Lucy & Ricky – I Love Lucy
9) Callie & Arizona – Grey’s Anatomy
10) Naomi & Emily - Skins
11) Laura & Adama - Battlestar Galactica
12) Grissom & Sara – CSI
13) Chandler & Monica – Friends
14) Ned & Charlotte – Pushing Daisies
15) Bette & Tina – The l Word
16) Bill & Sookie - True Blood
17) Miranda & Steve – Sex and the City
18) Katherine & Robin – Desperate Housewives
19) Turk & Carla – Scrubs
20) Castle & Beckett – Castle
21) Carla & Hanna – Verboteneliebe
22) Sam & Diane – Cheers
23) Cook & Effy - Skins
24) Mulder & Skully – The X Files
25) Xena & Gabrielle - Xena: Warrior Princess

Glee:
1. Jesse/Rachel
2. Sam/Quinn
3. Brittany/Santana
4. Puck/Rachel

90210:
5. Liam/Annie
6. Navid/Silver
7. Raj/Ivy

GG:
8. Nate/Jenny
9. Dan/Serena
10. Carter/Serena
11. Chuck/Blair

OTH:
12. Lucas/Brooke
13. Nathan/Haley
14. Jake/Peyton
15. Julian/Brooke

PLL:
16. Caleb/Hanna

Skins:
17. Sid/Cassie
18. Tony/Michelle
19. Chris/Jal
20. Cook/Effy
21. Emily/Naomi

TVD:
22. Damon/Elena
23. Elijah/Katherina
24. Tyler/Caroline

True Blood:
25. Eric/Sookie

*In order by show*
Glee
1. Puck/Rachel
2. Brittany/Artie
3. Jesse/Rachel
4. Blaine/Kurt
5. Tina/Mike
6. Finn/Santana

Gossip Girl
7. Serena/Nate
8. Chuck/Blair
9. Dan/Vanessa
10. Dan/Blair

Vampire Diaries
11. Stefan/Elena
12. Bonnie/Damon
13. Tyler/Caroline
14. Jeremy/Anna

Pretty Little Liars
15. Hanna/Caleb
16. Toby/Emily
17. Aria/Ezra
18. Spencer/Alex

Friday Night Lights
19. Tim/Lyla
20. Matt/Julie

Buffy
21. Angel/Buffy
22. Spike/Buffy

More Glee Couples
23. Sam/Quinn-Glee
24. Finn/Quinn

Last Couple:
Alaric/Jenna-Vampire Diaries

I <3333 all these couples!!!

1. Damon/Elena - TVD
2. Eric/Sookie - True Blood
3. Dan/Marti - Hellcats
4. Jackson/Lexie - Grey's Anatomy
5. Tony/Tea - Skins US
6. Katherine/Stefan - TVD
7. Caroline/Stefan - TVD
8. Tyler/Caroline - TVD
9. Brooke/Nathan - OTH
10. Mark/Lexie - Grey's Anatomy
11. Dan/Blair - GG
12. Chuck Blair - GG (S1-2)
13. Puck/Rachel - Glee
14. Liam/Annie - 90210
15. Brooke/Lucas - OTH
16. Quinn/Puck - Glee
17. Jesse/Rachel - Glee
18. Freddie/Effy - Skins
19. Ryan/Marissa - The OC
20. Hanna/Caleb - PLL
21. Spencer/Toby - PLL
22. Buffy/Angel - BTVS
23. Kelly/Dylan - BH 90210
24. Pacey/Joey - Dawsons Creek
25. Clark/Lana - Smallville

Other couples that are also important:
Katherine/Elijah - TVD
Rory/Jess - Gilmore Girls
Hannah/Ben - Secret Diary of a Call Girl
Jenny/Nate - GG
Chris/Cassie - Skins
Cook/Naomi - Skins
Alo/Mini - Skins
Ethan/Silver - 90210
Naomi/Oscar - 90210
Mini/Nick - Skins

booth/bones {bones}
chuck/blair {gossip girl}
house/cuddy {house md}
clark/lois {smallville}
buffy/angel {BTVS}
tony/ziva {ncis}
alex/izzie {greys anatomy}
stefan/elena {TVD}
quinn/puck {glee}
monica/chandler {friends}
serena/nate {gossip girl}
brooke/lucas {OTH}
tony/michelle {24}
jackie/hyde {that 70's show}
ross/rachel {friends}
barney/robin {HIMYM}
mark/lexie {greys anatomy}
cook/effy {skins}
danny/lindsey {csi ny}
dan/blair {gossip girl}

plus others.

1. Rose&Ten <3 (Doctor Who)
2. Stefan&Elena (The Vampire Diaries)
3. Nathan&Haley (One Tree Hill)
4. Amy&Rory (Doctor Who)
5. Chuck&Blair (Gossip Girl)
6. Rory&Jess (Gilmore Girls)
7. Lucas&Peyton (One Tree Hill)
8. Chase&Cameron (House MD)
9. Marissa&Ryan (The OC)
10. Damon&Katherine (The Vampire Diaries)
11. Chuck&Sarah (Chuck)
12. Brooke&Julian (One Tree Hill)
13. Lorelai&Christopher (Gilmore Girls)
14. Seth&Summer (The OC)
15. Matt&Caroline (The Vampire Diaries)
16. Logan&Veronica (Veronica Mars)
17. Nate&Jenny (Gossip Girl)
18. Sydney&Vaughn (Alias)
19. Ross&Rachel (Friends)
20. House&Cuddy (House MD)
21. Rory&Logan (Gilmore Girls)
22. Clay&Quinn (One Tree Hill)
23. Damon&Bonnie (The Vampire Diaries)
24. Brooke&Lucas (One Tree Hill)
25. Peyton&Jake (One Tree Hill)

1. Brenda and Dylan (BH90210)
2. Buffy and Angel (BTVS)
3. Lucas and Peyton (OTH)
4. Haley and Nathan (OTH)
5. Brooke and Julian (OTH)
6. Izzie and Alex (GA)
7. Meredith and Derek (GA)
8. Damon and Elena (TVD)
9. Stefan and Katherine (TVD)
10. Caroline and Matt (TVD)
11. Claire and Phil (Modern Family)
12. Sookie and Eric (True Blood)
13. Liam and Annie (90210)
14. Caroline and Tyler (TVD)
15. Sabrina and Harvey (STTW)
16. Rachel and Ross (Friends)
17. Monica and Chandler (Friends)
18. Cassie and Jake (TSC)
19. Dianna and Adam (TSC)
20. Mitchell and Cameron (Modern Family)
21. Carrie and Big (SATC)
22. Charlotte and Harry (SATC(+
23. Melinda and Jim (GW)
24. Quinn and Puck (Glee)
25. Dan and Serena (GG)

1.Pacey and Joey (Dawson's Creek)
2.Logan and Veronica (Veronica Mars)
3.Spike and Buffy (BTVS)
4.Evan and Casey (Greek)
5.Tim and Lyla (FNL)
6.Peter and Olivia (Fringe)
7.Kelly and Dylan (BH 90210)
8.Klaus and Caroline (TVD)
9.Thayer and Emma (TLG)
10.Daniel and Emily (Revenge)
11.Jenna and Matty (Awkward)
12.Ben and Felicity (Felicity)
13.Skye and Lucas (Terra Nova)
14.Serena and Nate (GG)
15.Marian and Guy (Robin Hood)
16.Kai and Erica (Being Erica)
17.David and Maddie (Moonlighting)
18.Wade and Zoey (Hart of Dixie)
19.Annie and Jeff (Community)
20.Hanna and Caleb (PLL)
21.Annie and Liam (90210)
22.Castle and Beckett (Castle)
23.Tony and Ziva (NCIS)
24.Mark and Lexie (Grey's Anatomy)
25.Mal and Inara (Firefly)

1. Angel/Cordelia (Angel)
2. Sebastian/Rachel (Revolution)
3. Harry/Hermione (Harry Potter)
4. Booth/Brennan (Bones)
5. Mulder/Scully (The X-Files)
6. Barney/Robin (HIMYM)
7. Sheldon/Penny (The Big Bang Theory)
8. Cal/Gillian (Lie to me)
9. Damon/Elena (The Vampire Diaries)
10. Charlie/Claire (Lost)
11. Jack/Kate (Lost)
12. Xander/Willow (Buffy)
13. Cary/Kalinda (The Good Wife)
14. House/Cuddy (House MD)
15. Jin/Sun (Lost)
16. Dean/Bela (Supernatural)
17. Klaus/Katherine (The Vampire Diaries)
18. Chase/Thirteen (House MD)
19. Leonard/Amy (The Big Bang Theory)
20. Spike/Buffy (Buffy)
21. Hodgins/Cam (Bones)
22. Wilson/Cuddy (House MD)
23. Drogo/Dany (Game of Thrones)
24. Will/Alicia (The Good Wife)
25. Eli/Diane (The Good Wife)

I have so many new favorite couples lately so I thought I had to update! :)
Couldn't get down to just 25 so I entered 31 couples.

01. Damon & Elena - Vampire Diaries
02. Caroline & Klaus - Vampire Diaries
03. Jake & Cassie - The Secret Circle
04. Franky & Nick - Skins
05. Zoey & Wade - Hart of Dixie.
06. Mark & Lexie - Grey's Anatomy
07 Thayer & Emma - The Lying Game
08. Annie & Liam - 90210
09. Jason & Aria - Pretty Little Liars
10. Eric & Sookie - True Blood
11. Amy & Ephram - Everwood
12. Freddie & Effy - Skins
13. Brooke & Lucas- OTH
14. Marti & Dan - Hellcats
15. Alo & Mini - Skins
16. Jake & Marley - Glee
17. Quinn & Puck - Glee
18. Rachel & Brody - Glee
19. Tony & Tea - Skins US
20. Buffy & Angel - Buffy The Vampire Slayer
21. Kelly & Dylan - Beverly Hills 90210
22. Pacey & Joey - Dawson's Creek
23. Barney & Robin - How I Met Your Mother
24. Lana & Clark - Smallville
25. Ryan & Marissa - The OC
26. Emily & Daniel - Revenge
27. Emily & Aiden - Revenge
28. Stefan & Katherine - The Vampire Diaries
29. Dan & Blair - Gossip Girl
30. Chuck & Blair - Gossip Girl
31. Nate & Jenny - Gossip Girl

Not in order:
1. Hotch and Emily- Criminal Minds (Current OTP)
2. Riker and Troi- Star Trek: The Next Generation
3. Harm and Mac- JAG
4. Kira and Odo- Star Trek: Deep Space Nine
5. Piper and Leo- Charmed
6. House and Cuddy- House, M.D.
7. Mac and Stella- CSI: New York
8. Elliot and Olivia- Law & Order: Special Victims Unit
9. Castle and Beckett- Castle
10. Booth and Brennan- Bones
11. Jane and Lisbon- The Mentalist
12. Pete and Myka- Warehouse 13
13. Michaela and Sully- Dr. Quinn, Medicine Woman
14. Tony and Kate- NCIS
15. Mulder and Scully- The X Files
16. Callen and Kensi- NCIS: Los Angeles
17. Jordan and Garrett- Crossing Jordan
18. Emma and Graham- Once Upon a Time
19. Tony and Ziva- NCIS
20. Morgan and Garcia- Criminal Minds
21. Rumpelstiltskin and Belle- Once Upon a Time
22. Grissom and Willows- CSI
23. Reid and JJ- Criminal Minds
24. Danny and Lindsay- CSI: New York
25. Snow White and Prince Charming- Once Upon a Time

1.Sawyer and Kate (Lost)
2.The Doctor and Rose (Doctor Who)
3.Ross and Reachel (Friends)
4.Lee and Kara (BSG)
5.Tim and Lyla (FNL)
6.Luke and Lorelai (GG)
7.Jackie and Hyde (T70S)
8.Jeff and Britta (Community)
9.Lily and Cullen (Hell on Wheels)
10.Mal and Inara (Firefly)
11.Eric andSookie (True Blood)
12.JD and Elliot (Scrubs)
13.Freddy/Effy (Skins)
14.Castle and Beckett (Castle)
15.Cook and Effy (Skins)
16.Penny and Sheldon (TBBT)
17.Jess and Nick (New Girl)
18.Peter and Olivia (Fringe)
19.Monica and Chandler (Friends)
20.Dan and Blair (GG)
21.Ted and Robin (HIMYM)
22.Carrie and Aidan (SATC)
23.Damon & Elena (Vampire Diaries)
24.Annie and Abed (Community)
25.Wade and Zoey (Hart of Dixie)

Okay! At The Moment:
{1} Lucas/Peyton {One Tree Hill}
{2} Ryan/Marissa {The O.C.}
{3} Neal/Sara {White Collar}
{4} Nathan/Haley {One Tree Hill}
{5} Barney/Robin {How I Met Your Mother}
{6} Tyler/Caroline {The Vampire Diaries}
{7} Seth/Summer {The O.C.}
{8} Chuck/Blair {Gossip Girl}
{9} Nate/Serena {Gossip Girl}
{10} Julian/Brooke {One Tree Hill}
{11} Damon/Elena {The Vampire Diaries}
{12} Jack/Kate {Lost}
{13} Ezra/Aria {Pretty Little Liars}
{14} Clay/Quinn {One Tree Hill}
{15} Stefan/Caroline {The Vampire Diaries}
{16} Wade/Zoe {Hart Of Dixie}
{17} Stefan/Rebekah {The Vampire Diaries}
{18} Nick/Jess {New Girl}
{19} Toby/Spencer {Pretty Little Liars}
{20} Caleb/Hanna {Pretty Little Liars}
{21} Damon/Rebekah {The Vampire Diaries}
{22} Dodger/Texas {Hollyoaks}
{23} Klaus/Caroline {The Vampire Diaries}
{24} Sawyer/Kate {Lost}
{25} Merlin/Morgana {Merlin}

1. Damon & Elena (TVD)
2. Stefan & Katherine (TVD)
3. Chuck & Blair (GG)
4. Freedie & Effy (Skins)
5. Lucas & Peyton (OTH)
6. Quinn & Puck (Glee)
7. Serena & Carter (GG)
8. Jake & Cassie (TSC)
9. Zoe & Wade (Hart Of Dixie)
10. Brooke & Julian (OTH)
11. Buffy & Spike (BTVS)
12. Castle & Beckett (Castle)
13. Sawyer & Juliet (Lost)
14. Sawyer & Kate (Lost)
15. Merlin & Morgana (Merlin)
16. Barney & Robin (HIMYM)
17. House & Cuddy (House MD)
18. Mark & Lexi (Grey's Anatomy)
19. Liam & Naomi (90210)
20. Spencer & Toby (PLL)

only 20

At the moment...

1. Nathan & Haley (One Tree Hill)
2. Stefan & Elena (The Vampire Diaries)
3. Clark & Lois (Smallville)
4. Ryan & Taylor (The OC)
5. Barney & Robin (How I Met Your Mother)
6. Finn & Rachel (Glee)
7. Toby & Spencer (Pretty Little Liars)
8. Lucas & Peyton (One Tree Hill)
9. Nate & Serena (Gossip Girl)
10. Seth & Summer (The OC)
11. Matt & Caroline (The Vampire Diaries)
12. Ezra & Aria (Pretty Little Liars)
13. Marshall & Lily (How I Met Your Mother)
14. Wade & Zoe (Heart of Dixie)
15. Liam & Annie (90210)
16. Chad & Sonny (Sonny With A Chance)
17. Chace & Cameron (House MD)
18. Julian & Brooke (One Tree Hill)
19. Puck & Quinn (Glee)
20. Sheldon & Penny (The Big Bang Theory)
21. Hodgins & Angela (Bones)
22. House & Cuddy (House MD)
23. Oliver & Chloe (Smallville)
24. Booth & Bones (Bones)
25. Chuck & Blair (Gossip Girl)

1. Sheldon & Amy (The Big Bang Theory)
2. Jim & Pam (The Office (US))
3. Castiel & Meg (Supernatural)
4. Leonard & Penny (The Big Bang Theory)
5. Charlie & Claire (Lost)
6. Drogo & Daenerys (Gams of Thrones)
7. Andy & Erin (The Office (US))
8. Tyrion & Shae (Game of Thrones)
9. Howard & Bernadette (The Big Bang Theory)
10. Ross & Rachel (Friends)
11. Chandler & Monica (Friends)
12. Joey & Phoebe (Friends)
13. François & Denise (Omertà: La Loi du Silence)
14. Spock & Uhura (Star Trek: The Original Series)
15. Kirk & Janice (Star Trek: The Original Series)
16. Gendry & Arya (Game of Thrones) WHEN SHE'LL BE OLDER, NOT NOW
17. Sawyer & Juliet (Lost)
18. Jack & Kate (Lost)
19. George-Michael & Maeby (Arrested Development) , they're not real cousin after all LOL
20. Hyde & Jackie (That '70s Show)
21. Eric & Donna (That '70s Show)
22. Spike & Buffy (Buffy the Vampire Slayer)
23. Xander & Willow (Buffy the Vampire Slayer)
24. Nick & Lindsay (Freaks and Geeks)
25. Sam & Jessica (Supernatural)

maybe not in that order exactly, a lot are tie, but those are my top 25

In no particular order:

1. Spike & Buffy (Buffy the Vampire Slayer)
2. Oz & Willow (Buffy the Vampire Slayer)
3. Nate & Serena (Gossip Girl)
4. Chuck & Blair (Gossip Girl)
5. Vince & Holly (What I Like About You)
6. Seth & Summer (The OC)
7. Pacey & Joey (Dawson's Creek)
8. Stefan & Caroline (TVD)
9. Damon & Elena (TVD)
10. Alex & Izzie (Grey's Anatomy)
11. Derek & Meredith (Grey's Anatomy)
12. Cappie & Casey (Greek)
13. Jake & Jenna (Awkward.)
14. Matthew & Mary (Downton Abbey)
15. Daniel & Emily/Amanda (Revenge)
16. Chandler & Monica (FRIENDS)
17. Joey & Rachel (FRIENDS)
18. House & Cuddy (House MD)
19. Chase & Cameron (House MD)
20. Mike & Susan (Desperate Housewives)
21. Ryan & Marissa (The OC)
22. Eric & Calleigh (CSI: Miami)
23. Wren & Spencer (PLL)
24. Jason & Aria (PLL)
25. Mike & Phoebe (FRIENDS)

My top couples:
1. Lucas & Peyton {One Tree Hill}
2. Clark & Lana {Smallville}
3. Jack & Kate {Lost}
4. Piper & Leo {Charmed}
5. Ryan & Marissa {OC}
6. Seth & Summer {OC}
7. Nathan & Haley {One Tree Hill}
8. Phoebe & Cole {Charmed}
9. Dawson & Joey {Dawson’s Creek}
10. Buffy & Spike {Buffy Vampire Slayer}
11. House & Cameron {Dr.House}
12. Tom & Lynette {Desperate Housewives}
13. Susan & Mike {Desperate Housewives}
14. Buffy & Angel {Buffy Vampire Slayer}
15. Xander & Anya {{Buffy Vampire Slayer}}
16. Maria & Tony {Terra Nostra 2}
17. Pedro & Silvia {Paso Adelante}
18. Charlie & Claire {Lost}
19. Desmond & Penny {Lost}
20. Jake & Peyton {One Tree Hill}
21. Lorelai & Christopher {Gilmore Girls}
22. Rory & Dean {Gilmore Girls}
23. Dylan & Brenda {Beverly Hills}
24. Oliver & Chloe {Smallville}

They are not in order, except the first three. I have to watch Gossip Girl, the Vampire Diaries & Friends so maybe my list can change.

One tree hill: Brooke/Lucas<33333 (My OTP), Nathan and Haley, Peyton and Jake
The o.c: ryan/Marissa(My second favoite cople), Seth/Summer
Gossip Girl: Dan/Serena, Chuck/Blair, Nate/Jenny ( but I love Dairs Friendship)
the vampire diaries:Stefan/ Caroine ( XD), Damon/Elena, Caroline/Klaus, Bonny/Jeremy
90210: Silver/Navid, Annie/ Liam
Pretty little liars: Toby/Spencer, Hannah/Caleb,
Glee:Quinn/Puck, rachel /Brody ( I know this is embarassing), Brittany/Santana, Kurt/Blaine
Gilmore girls: rory/Jess, Luke/Lorelai
Lost: Sawyer/Kate
feinds: Monica + Chandler, Ross/Rachel

In order by show

01. Monica + Chandler (Friends)
02. Mark + Lexie (GA)
03. Leonard + Penny (TBBT)
04. Ross + Rachel (Friends)
05. Piper + Leo (Charmed)
06. Callie + Arizona (GA)
07. Niles + CC (Nanny)
08. Nate + Serena (GG)
09. Mike + Phoebe (Friends)
10. Howard + Bernadette (TBBT)
11. Mike + Susan (DH)
12. Meredith + Derek (GA)
13. Sheldon + Amy (TBBT)
14. Toni + Ziva (NCIS)
15. Marshall + Lily (HIMYM)
16. Jackson + April (GA)
17. Fran + Maxwell (Nanny)
18. Stefan + Elena (TVD)
19. Lily + Scotty(CC)
20. Phoebe + Cole (Charmed)
21. Pete + Addison (PP)
22. Alex + Izzie(GA)
23. Samantha + Smith (SatC)
24. Matt + Caroline (TVD)
25. Abby + McGee(NCIS),

IMPORTANT TO MENTION : Dan/Vanessa,Chuck&Blair,Dan&Serena­,Na­te&­amp­;Bl­air (GG), Monica&Richard, Chandler&Janice(friends), Teddy&Henry, Cristina&Owen, Jackson&Lexie, Izzie&Denny, Mark&Addison(GA), Prue&Andy, Paige&Henry(Charmed), Leyton/Naley/Brucas (OTH), Tom&Lynette, Carlos&Gaby (DH), Jeremy&Bonnie, Damon&Elena, Stefan&Rebekah, Tyler&Caroline (TVD), Carrie&Aidan, Charlotte&Henry, Carrie&Big, Miranda&Steve(SatC), Walden&Zoe, Charlie&Rose(2 + 1/2 Men), Matt&Summer(Baywatch), Barney&Robin {HIMYM}

I can't put them in any 'ranking' ...they are in particular order :)

Friends:
Ross and Rachel
Monica and Chandler
Phoebe and Mike
Joey and Phoebe (as friends)

Castle:
Castle and Beckett
Espo and Lanie
Jenny and Ryan

Gilmore Girls:
Luke and Lorelai

Go On:
Ryan and Lauren

HIMYM:
Robin and Barney
Lily and Marshall
Ted and THE MOM

X-files:
Mulder and Scully

Nashville:
Rayna and Deacon ( I'm currently obsessed with them :))

Grey's Anatomy:
Christina and Owen
Callie and Arizona
Callie and Mark (friends)
Henry and Teddy
Mer and Derek
Addie and Mark
Carev and Jo

Law and Order : Svu:
Liv and El

Bones:
Bones and Booth

Ncis: LA:
Deeks and Kensi
Nel and Eric

Gossip Girl:
Rufus and Lily

Lie to me:
Cal and Gillian

Desperate Housewives:
Gabby and Calos
Tom and Lynette
Mike and Susan

Criminal Minds:
Morgan and Emily
JJ and Will
Reid and Emily ( friends)
Penelope and Morgan( friends)

Suits:
Harvey and Donna

New girl:
Nick and Jess


Sex and the city:
Carrie and Big

House:
House and Cuddy

:))

OK, I made some changes so here's my NEW list
_________________________________________­_

{01} Monica & Chandler | Friends ♥
{02} Mark & Lexie | Grey's Anatomy ♥
{03} Leonard & Penny | The Big Bang Theory ♥
{04} Piper & Leo | Charmed ♥
{05} Ross & Rachel | Friends ♥
{06} Callie & Arizona | Grey's Anatomy ♥
{07} Niles & CC | The Nanny ♥
{08} Will & Emma | Glee ♥
{09} Joey & Phoebe | Friends ♥
{10} Howard & Bernadette | The Big Bang Theory ♥
{11} Jackson & April | Grey's Anatomy ♥
{12} Nate & Serena | Gossip Girl ♥
{13} Mike & Susan | Desperate Housewives ♥
{14} Sheldon & Amy | The Big Bang Theory ♥
{15} Marshall & Lily | How I Met Your Mother ♥
{16} Tony & Ziva | NCIS ♥
{17} Meredith & Derek | Grey's Anatomy ♥
{18} Mike & Phoebe | Friends ♥
{19} Phoebe & Cole | Charmed ♥
{20} Steve & Miranda | Sex & The City ♥
{21} Alex & Izzie | Grey's Anatomy ♥
{22} Stefan & Elena | The Vampire Diaries ♥
{23} Puck & Quinn | Glee ♥
{24} Fran & Maxwell | The Nanny ♥
{25} Lily & Scotty | Cold Case ♥ // Ezra & Aria | Pretty Little Liars ♥
__________________________________________­_

So this is my updated version!
1; Lucas•Peyton (One Tree Hill)
2; Sawyer•Juliet (Lost)
3; Nathan•Haley (One Tree Hill)
4; Neal•Sara (White Collar)
5; Jack•Kate (Lost)
6; Barney•Robin (How I Met Your Mother)
7; Tyler•Caroline (The Vampire Diaries)
8; Damon•Elena (The Vampire Diaries)
9; Derek•Meredith (Grey's Anatomy)
10; Mark•Addison (Grey's Anatomy)
11; Chuck•Blair (Gossip Girl)
12; Ryan•Marissa (The OC)
13; Nate•Serena (Gossip Girl)
14; Seth•Summer (The OC)
15; Alex•Izzie (Grey's Anatomy)
16; Stefan•Rebekah (The Vampire Diaries)
17; Klaus•Caroline (The Vampire Diaries)
18; Wade•Zoe (Hart of Dixie)
19; Nick•Jess (New Girl)
20; Graham•Emma (Once Upon A Time)
21; Sawyer•Kate (Lost)
22; Toby•Spencer (Pretty Little Liars)
23; Julian•Brooke (One Tree Hill)
24; Stefan•Caroline (The Vampire Diaries)
25; Ezra•Aria (Pretty Little Liars)

#1: ross&rachel // friends
#2: lucas&peyton // one tree hill
#2: meredith&derek // grey's anatomy (yes both LP and MD are my 2nd faves)
#4: robin&barney // himym
#5: neal&sara // white collar
#6: snow&charming // ouat
#7: castle&beckett // castle
#8: rachel&finn // glee
#9: monica&chandler // friends
#10: alex&izzie // grey's anatomy
#11: carrie&aidan // sex&the city
#12: nathan&haley // one tree hill
#13: steve&miranda // sex&the city
#14: will&emma // glee
#15: owen&cristina // grey's anatomy
#16: brooke&julian // one tree hill
#17: callie&arizona // grey's anatomy
#18: dan&serena // gossip girl
#19: jules&grayson // cougar town
#20: phoebe&mike // friends
#21: graham&emma // ouat
#22: jackson&april // grey's anatomy
#23: puck&quinn // glee
#24: nick&jess // new girl
#25: alex&addison // grey's anatomy

Updated

01 ♥ Monica & Chandler {friends}
02 ♥ Mark & Lexie {grey's anatomy}
03 ♥ Piper & Leo {charmed}
04 ♥ Leonard & Penny {the big bang theory}
05 ♥ Nathan & Haley {one tree hill}
06 ♥ Ross & Rachel {friends}
07 ♥ Jackson & April {grey's anatomy}
08 ♥ Brittany & Santana {glee}
09 ♥ Barney & Robin {how I met your mother}
10 ♥ Nick & Jess {new girl}
11 ♥ Callie & Arizona {grey's anatomy}
12 ♥ Niles & CC {the nanny}
13 ♥ Kurt & Blaine {glee}
14 ♥ Howard & Bernadette {the big bang theory}
15 ♥ Steve & Miranda {sex & the city}
16 ♥ Sheldon & Amy {the big bang theory}
17 ♥ Nate & Serena {gossip girl}
18 ♥ Brooke & Lucas {one tree hill}
19 ♥ Meredith & Derek {grey's anatomy}
20 ♥ Marshall & Lily {how I met your mother}
21 ♥ Alex & Izzie {grey's anatomy}
22 ♥ Sam & Quinn {glee}
23 ♥ Tony & Ziva {ncis}
24 ♥ Mike & Susan {desperate housewives}
25 ♥ Phoebe & Mike {friends}

Honorable Mention ♥ Lucas & Peyton / Will & Emma / Teddy & Henry ♥

1. Finn and Rachel-Glee
2. Puck and Rachel-Glee
3.Jackie and Hyde-That '70s Show
4.Aria and Ezra-Pretty Little Liars
5.Ross and Rachel-Friends
6.Chuck and Blair-Gossip Girl
7.Kitty and Ryder-Glee
8.Spencer and Toby-Pretty Little Liars
9.Kurt and Blaine-Glee
10.Brittany and Santana-Glee
11.Penny and Leonard-The Big Bang Theory
12.Barney and Robin-How I Met Your Mother
13.Holly and Vince-What I Like About You
14.Quinn and Sam-Glee
15.Monica and Chandler-Friends
16.Dan and Serena-Gossip Girl
17Nate and Blair-Gossip Girl
18.Marley and Ryder-Glee
19.Pheobe and Mike-Friends
20.Tony and Ziva-NCIS
21.Shawn and Juliet-Psych
22.Hanna and Caleb-Pretty Little Liars
23.Marshall and Lily-How I Met Your Mother
24.Donna and Eric-That '70s Show
25.Damon and Emily-Make It Or Break It

1. mulder&scully (the x files)
2. kate&sawyer (lost)
3. veronica&logan (veronica mars)
4. spike&buffy (btvs)
5. sydney&vaughn (alias)
6. jeff&annie (community)
7. lucas&peyton (one tree hill)
8. quinn&rachel (glee)
9. seth&summer (the oc)
10. stiles&lydia (teen wolf)
11. lexie&mark (grey's anatomy)
12. eric&sookie (true blood)
13. rory&jess (gilmore girls
14. luke&lorelai (gilmore girls)
15. quinn&puck (glee)
16. nathan&haley (one tree hill)
17. desmond&penny (lost)
18. alex&izzie (grey's anatomy)
19. ryan&marissa (the oc)
20. stiles&derek (teen wolf)
21. hoyt&jessica (true blood)
22. willow&tara (btvs)
23. britta&troy (community)
24. jaime&brienne (game of thrones)
25. jin&sun (lost)

In no particular order:

01) Dean and Castiel (Supernatural)
02) Damon and Elena (The Vampire Diaries)
03) Chuck and Blair (Gossip Girl)
04) Klaus and Caroline (The Vampire Diaries)
05) Spike and Buffy (Buffy The Vampire Slayer)
06) Angel and Cordelia (Angel The Series)
07) Stiles and Lydia (Teen Wolf)
08) Wesley and Fred (Angel The Series)
09) Cole and Phoebe (Charmed)
10) Booth and Brennan (Bones)
11) Seth and Summer (The O.C.)
12) Peter and Claire (Heroes) -> in AU
13) Blaine and Kurt (Glee)
14) Leo and Piper (Charmed)
15) Rory and Amy (Doctor Who)
16) Barney and Robin (How I Met Your Mother)
17) Mulder and Scully (The X Files)
18) Xander and Anya (Buffy The Vampire Slayer)
19) Ten and Rose (Doctor Who)
20) Peter and Olivia (Fringe)
21) Castiel and Meg (Supernatural)
22) Wesley and Lilah (Angel The Series)
23) Hodgins and Angela (Bones)
24) Eleven and River (Doctor Who)
25) Sweets and Daisy (Bones)

1. Ross & Rachel (Friends)
2. Lucas & Peyton (OTH)
3. Puck & Quinn (Glee)
4. Dan & Blair (GG)
5. Mark & Lexie (GA)
6. Stefan & Katherine (TVD)
7. Cook & Effy (Skins)
8. Jackson & April (GA)
9. Jake & Peyton (OTH)
10. Caroline & Tyler (TVD)
11. Kate & Gibbs (NCIS)
12. Brooke & Lucas (OTH)
13. Mcgee & Abby (NCIS)
14. Mary & Matthew (Downton Abbey)
15. Monica & Chandler (Friends)
16. Sybil & Tom (Downton Abbey)
17. Olivia & Jake (Scandal)
18. Olivia & Fitz (Scandal)
19. Quinn & Rachel (Glee)
20. Mia & Chase (OTH)
21. Kurt & Sebastian (Glee)
22. Matt & Rebekah (TVD)
23. Alex & Addison (GA)
24. Katherine & Elijah (TVD)
25. Quinn & Finn (Glee)

super duper updated

#1; monica & chandler (friends)
#1; mark & lexie (ga)
#3; piper & leo (charmed)
#4; nathan & haley (oth)
#5; leonard & penny (tbbt)
#6; barney & robin (himym)
#7; brittany & santana (glee)
#8; ross & rachel (friends)
#9; nick & jess (ng)
#10; ezra & aria (pll)
#11; jackson & april (ga)
#12; callie & arizona (ga)
#13; niles & cc (nanny)
#14; spencer & toby (pll)
#15; brooke & julian (oth)
#16; kurt & blaine (glee)
#17; steve & miranda (satc)
#18; howard & bernadette (tbbt)
#19; sheldon & amy (tbbt)
#20; hanna & caleb (pll)
#21; sam & quinn (glee)
#22; nate & serena (gg)
#23; alex & izzie (ga)
#24; marshall & lily (himym)
#25; tony & ziva (ncis)

My list is updated as well !

1. ross&rachel {friends}
2. castle&beckett {castle}
3. lucas&peyton {one tree hill}
4. derek&meredith {grey's anatomy}
5. barney&robin {himym)
6. neal&sara {white collar}
7. snow&charming {ouat}
8. steve&miranda {satc}
9. finn&rachel {glee}
10. monica&chandler {friends}
11. carrie&aidan {satc}
12. alex&izzie {grey's anatomy}
13. callie&arizona {grey's anatomy}
14. will&emma {glee}
15. dan&serena {gossip girl}
16. tyler&caroline {tvd}
17. nathan&haley {one tree hill}
18. brooke&julian {one tree hill}
19. graham&emma {ouat}
20. cristina&owen {grey's anatomy}
21. puck&quinn {glee}
22. clay&quinn {one tree hill}
23. rumelstiltskin&belle {ouat}
24. phoebe&mike {friends}
25. big&carrie {satc}

They're not necessarily in order, but...

1. Chop/Izzy (My Mad Fat Diary)
2. Stiles/Lydia (Teen Wolf)
3. Damon/Elena (The Vampire Diaries)
4. Toby/Spencer (Pretty Little Liars)
5. Barney/Robin (How I Met Your Mother)
6. TomTom/Jess (By Any Means)
7. Chuck/Blair (Gossip Girl)
8. Nate/Blair (Gossip Girl)
9. Chandler/Monica (Friends)
10. Eric/Sookie (True Blood)
11. Hook/Emma (Once Upon a Time)
12. Rumple/Belle (Once Upon a Time)
13. Jeremy/Anna (The Vampire Diaries)
14. Klaus/Hayley (The Vampire Diaries/The Originals)
15. Elijah/Elena (The Vampire Diaries)
16. Derek/Lydia (Teen Wolf)
17. Graham/Emma (Once Upon a Time)
18. Kurt/Blaine (Glee)
19. Drew/Denise (Scrubs)
20. Pacey/Joey (Dawson's Creek)
21. Charlie/Jess (By Any Means)
22. Bass/Charlie (Revolution)
23. Adam/Charlie (Revolution)
24. Jason/Charlie (Revolution)
25. Miles/Rachel (Revolution)

1) Buffy & Spike (Buffy the Vampire Slayer)
2) Damon & Elena (The Vampire Diaries)
3) Clark & Lois (Smallville)
4) Stefan & Katherine (The Vampire Diaries)
5) Captain Hook & Emma (Once Upon A Time)
6) Chuck & Blair (Gossip Girl)
7) Angel & Cordelia (Angel)
8) Chloe & Oliver (Smallville)
9) Hanna & Caleb (Pretty Little Liars)
10) Lex & Lana (Smallville)
11) Tyler & Caroline (The Vampire Diaries)
12) Jeremy & Bonnie (The Vampire Diaries)
13) Spencer & Toby (Pretty Little Liars)
14) Ezra & Aria (Pretty Little Liars)
15) EJ & Sami (Days of our Lives)
16) Rumplestiltskin & Belle (Once Upon A Time)
17) Fred & Wesley (Angel)
18) Eric & Sookie (True Blood)
19) Xander & Anya (Buffy the Vampire Slayer)
20) Snow White & Prince Charming (Once Upon A Time)
21) Pacey & Joey (Dawson's Creek)
22) Willow & Oz (Buffy the Vampire Slayer)
23) Dan & Serena (Gossip Girl)
24) Stefan & Caroline (The Vampire Diaries)
25) Dante & Lulu (General Hospital)

In no particular order (except for Destiel, Merthur, and Joanlock, which will always be my top 3)

1. Dean/Castiel - Supernatural
2. Merlin/Arthur - Merlin
3. Sherlock/Joan - Elementary
Oliver/Felicity - Arrow
Jack/Emily - Revenge
Ten/Rose - Doctor Who
Castle/Beckett - Castle
Sam/Gabriel - Supernatural
Sokka/Suki - Avatar: The Last Airbender
Monroe/Rosalee - Grimm
Toph/The Duke - Avatar: The Last Airbender
Bones/Booth - Bones
Lorelai/Luke - Gilmore Girls
Rory/Jess - Gilmore Girls
Rory/Logan - Gilmore Girls
Lane/Zach - Gilmore Girls
Leonard/Penny - The Big Bang Theory
Sheldon/Amy - The Big Bang Theory
Clark/Lana - Smallville
Tony/Ziva - NCIS
Abby/McGee - NCIS
Neal/Sarah - White Collar
Peter/Elizabeth - White Collar
Barney/Robin - How I Met Your Mother
Merlin/Freya - Merlin

It changes a lot (except for the top few)
At this time (I legit keep a list of my top 30 on word:
1.Rumpelstiltskin and Belle (Once Upon a Time)
2.Dean and Castiel (Supernatural)
3.The Doctor/River (Doctor Who)
4.Emma and Killian (Once Upon a Time)
5.Klaus and Caroline (Vampire Diaries)
6.Barney and Robin (How I Met Your Mother)
7.Jack and Ianto (Torchwood)
8.Cordelia and Angel (Angel)
9.Oliver and Felicity (Arrow)
10.Victor and Ruby (Once Upon a Time)
11.Sansa and Sandor (Game of Thrones)
12.Logan and Veronica (Veronica Mars)
13.Buffy and Spike (Buffy the Vampire Slayer)
14.Mulan and Aurora (Once Upon a Time)
15.Jaime and Brienne (Game of Thrones)
16.Hayley and Elijah (The Originals)
17.Kenzi and Vex (Lost Girl)
18.Bo and Lauren (Lost Girl)
19.Emily and Nolan (Revenge)
20.Robin and Marian (BBC Robin Hood)
21.Monica and Chandler (Friends)
22.Malcolm and Inara (Firefly)
23.Vic and Val (What I Like About You)
24.Amy and Rory (Doctor Who)
25.Jackie and Hyde (That 70's Show)

Rounding out my top 30:
26.Wesley and Lilah (Angel)
27.Xander and Anya (Buffy the Vampire Slayer)
28.Jon and Ygritte (Game of Thrones)
29.Jess and Becker (Primeval)
30.Connor and Abby

Were these supposed to be canon? If they were, sorry not sorry.

1. Damon & Elena (The Vampire Diaries)
2. Veronica & Logan (Veronica Mars)
3. Brooke & Lucas (One Tree Hill)
4. Serena & Nate (Gossip Girl)
5. Liam & Annie (90210)
6. Quinn & Puck (Glee)
7. Pacey & Joey (Dawson's Creek)
8. Oliver & Felicity (Arrow)
9. Stefan & Caroline (The Vampire Diaries)
10. Spencer & Toby (Pretty Little Liars)
11. Neal & Sara (White Collar)
12. Ted & Robin (How I Met Your Mother)
13. Damon & Bonnie (The Vampire Diaries)
14. Emily & Daniel (Revenge)
15. Meredith & Derek (Grey's Anatomy)
16. Matthew & Mary (Downton Abbey)
17. Buffy & Angel (Buffy the Vampire Slayer)
18. Michael & Nikita (Nikita)
19. Hanna & Caleb (Pretty Little Liars)
20. Mary & Francis (Reign)
21. Kala & Wolfgang (Sense8)
22. Olivia & Fitz (Scandal)
23. Klaus & Caroline (The Vampire Diaries)
24. Scott & Allison (Teen Wolf)
25. Neal & Emma (Once Upon A Time)

Something like this, but the order isn't entirely precise :)

1.Finn and Rachel - Glee
2.Brooke and Lucas- One Tree Hill
3.Stefan and Caroline - The Vampire Diaries
4.Damon and Elena - The Vampire Diaries
5.Serena and Nate - Gossip Girl
6.Kurt and Blaine - Glee
7.Jake and Peyton - One Tree Hill
8.Dan and Blair - Gossip Girl
9.Dean and Castiel - Supernatural
10.Carrie and Big - Sex and the city
11.Spencer and Toby - Pretty Little Liars
12.Nathan and Haley - One Tree Hill
13.Monica and Chandler - Friends
14.Snow White and Charming - Once Upon A Time
15.Ross and Rachel - Friends
16.Hook and Emma - Once Upon A Time
17.Alex and Izzie -Grey's Anatomy
18.Piper and Leo -Charmed
19.Kate and Sawyer - Lost
20.Tyler and Caroline -The Vampire Diaries

updated one more time (it's getting ridiculous)

1/ Mark & Lexie (Grey's Anatomy)
2/ Chandler & Monica (Friends)
3/ Chuck & Blair (Gossip Girl)
4/ Nathan & Haley (One Tree Hill)
5/ Nick & Jess (New Girl)
6/ Leo & Piper (Charmed)
7/ Ezra & Aria (Pretty Little Liars)
8/ Brittany & Santana (Glee)
9/ Ross & Rachel (Friends)
10/ Leonard & Penny (The Big Bang Theory)
11/ Barney & Robin (How I Met Your Mother)
12/ Jackson & April (Grey's Anatomy)
13/ Hanna & Caleb (Pretty Little Liars)
14/ Spencer & Toby (Pretty Little Liars)
15/ Brooke & Julian (One Tree Hill)
16/ Stefan & Caroline (The Vampire Diaries)
17/ Naomi & Emily (Skins UK)
18/ Niles & CC (The Nanny)
19/ Nate & Serena (Gossip Girl)
20/ Steve & Miranda (Sex and the City)
21/ Callie & Arizona (Grey's Anatomy)
22/ Tony & Ziva (NCIS)
23/ Chris & Jal (Skins UK)
24/ Sheldon & Amy (The Big Bang Theory)
25/ Marshall & Lily (How I Met Your Mother

Honorable mentions:
- Jeff & Annie (Community)
- Sam & Quinn (Glee)
- Damon & Elena (The Vampire Diaries)

1. Dan & Blair [Gossip Girl]
2. Pacey & Joey [Dawson's Creek]
3. Stefan & Caroline [The Vampire Diaries]
4. Tim & Lyla [Friday Night Lights]
5. Liam & Annie [90210]
6. Sam & Rachel [Glee]
7. Ryan & Taylor [The OC]
8. Klaus & Hayley [The Originals]
9. Logan & Veronica [Veronica Mars]
10. Michael & Sara [Prison Break]
11. Clark & Lois [Smallville]
12. Jess & Rory [Gilmore Girls]
13. Zack & Kelly [Saved By the Bell]
14. Carter & Serena [Gossip Girl]
15. Dean & Jo [Supernatural]
16. Puck & Rachel [Glee]
17. Tommy & Lindy [Eye Candy]
18. Martin & Sam [Without a Trace]
19. Thayer & Emma [The Lying Game]
20. Deeks & Kensi [NCIS: LA]
21. Jeff & Annie [Community]
22. Avery & Juliette [Nashville]
23. Nathan & Peyton [One Tree Hill]
24. George & AnnaBeth [Hart of Dixie]
25. Jay & Manny [Degrassi: The Next Generation]
.

Toby & Happy [Scorpion]
Tony & Ziva [NCIS]
Jack & Sam [Stargate SG1]
Mulder & Scully [The X Files]

Sharon & Andy [Major Crimes]
Fitz & Simmons [Agents of Shield
Jake & Amy [B99]
Wynonna & Dolls [Wynonna Earp]
Waverly & Nicole [Wynonna Earp]
Root & Shaw [Person of Interest]
Niles & Daphne [Frasier]
Peter & Olivia [Fringe]
Piper & Leo [Charmed]
Hodgins & Angela [Bones]
John & Aeryn [Farscape]
Tom & B'Elanna [Star Trek: Voyager]
Chuck & Sarah [Chuck]
Deeks & Kensi [NCIS: LA]
Kara & James [Supergirl]
Hardison & Parker [Leverage]
Rick & Michonne [The Walking Dead]
Xander & Anya [BtVS]
Shane & Oliver [Signed, Sealed, Delivered]
Rita & Norma [Signed, Sealed, Delivered]
Clark & Lois [Smallville]

JUST THE FIRST FOUR ARE IN ORDER.