The one big difference between the Powerpuff Girls and the Rowdyruff Boys are their weaknesses. Though the Powerpuff Girls have been defeated before, they don't have any glaring weaknesses except when they are divided. The Rowdyruff Boys, on the other hand, have several significant weaknesses that they all share. Due to the boys' being having higher tolerance for damage than the girls, they are almost impossible to defeat in head-on combat, this is proven in their first encounter where they were the only ones that could defeat the Powerpuff girls in a fair fight, these weaknesses must constantly...